This is an alternative procedure which may be accepted by the FAA for patients who can not exercise on a treadmill.  Contact Pilot Medical Solutions to discuss the criteria for this option.

What is an IV Persantine-Thallium Stress Test?

  • This test is an alternative procedure for patients with coronary artery disease who can not exercise on a treadmill.
  • An IV line is started to administer the persantine and the thallium.
  • Persantine helps to expand the coronary arteries increasing the blood flow to the area. This effect is similar to what happens during vigorous exercise.
  • Thallium (a radioactive isotope) is detected by X-rays and shows which parts of the heart muscle are receiving enough oxygen.
  • Side effects of thallium are rare and may include rashes or low blood pressure.
  • Possible temporary side effects of Persantine may include: headache, dizziness, nausea/vomiting, chest discomfort.
  • Electrodes will be placed on the chest so that the heart rate and rhythm will be monitored by an electrocardiogram (EKG).
  • A special camera takes pictures of the heart.
  • This test is usually administered in 2 phases with each phase lasting 30-60 minutes. The patient may be required to return the following day to complete the second phase.
  • The phase of this test takes about 60 minutes.
  • This test must be ordered by the doctor.

Why is a Persantine Stress Performed?

  • This test will help the doctor to evaluate the patient’s cardiac condition related to:
    • Irregular heart rhythms
    • Which areas of the heart are not getting enough blood and oxygen.
    • How quickly the heart recovers after exercise.

What Preparation is Needed?

  • Nothing to eat or drink for 3 hours prior to the test.
  • Do not smoke or drink caffeine for at least 6 hours prior to the test.
  • It is important for the patient to ask his doctor:
    • how to adjust his insulin and food intake prior to the test if he is a diabetic
    • if he should take his regular medications on the morning of the test.
    • if he is on a Beta Blocker, can he STOP taking this medication 72 hours before the test as this is recommended for best results
  • If the patient is taking aminophylline or theodur, he must discontinue it for 48-72 hours prior to the test.
  • The patient must notify his physician if:
    • he is allergic to Theophylline or Persantine
    • he has asthma, chronic lung disease or any heart conditions
  • Do not apply lotions, oils or powders to the chest area.



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to confidentially discuss your FAA medical issues.